flupirtine hcl

Flupirtine HCl is the salt form of Flupirtine, also known as W-2964, an aminopyridine that functions as a centrally acting non-opioid analgesic. It first became available in Europe in 1984, and is sold mainly under the names Katadolon, Trancolong, Awegal, Efiret, Trancopal Dolo, and Metanor. Like nefopam, it is unique among analgesics in that it is a non-opioid, non-NSAID, non-steroidal centrally acting analgesic. Flupirtine is a selective neuronal potassium channel opener that also has NMDA receptor antagonist and GABAA receptor modulatory properties.

Flupirtine-D4 hydrochloride，Flupirtine hydrochloride的氘代物，为神经元钾通道开放剂，具有拮抗NMDA受体的作用。

Flupirtine(D 9998)是神经元钾通道的选择性开放剂，并且具有NMDA 受体拮抗剂的特性。

Flupirtine maleate (Katadolon maleate) 是可透过血脑屏障的、具有口服活性的非阿片类化合物。它是间接 NMDAR 拮抗剂，可用于缓解疼痛的研究，具有神经保护特性。