flumequine 13c3

Flumequine-13C3 is intended for use as an internal standard for the quantification of flumequine by GC- or LC-MS. Flumequine (T1060) is a fluoroquinolone antibiotic.1It is active againstS. aureus,S. pyogenes,B. subtilis,E. coli,P. aeruginosa,S. faecalis,andK. pneumoniae (MICs = 1-100 μg/ml). Flumequine (T1060) is also active against field isolates of B. hyodysenteriae (MICs = 6.25-200 μg/ml).2It inhibits DNA gyrase,disrupting supercoiling of bacterial DNA to block transcription and replication.3

Flumequine (R-802) 是一种喹诺酮类抗生素，对革兰氏阳性菌和革兰氏阴性菌均有效。它是拓扑异构酶 II 抑制剂， 抑制细胞分裂，IC50值为 15 μM (3.92 μg/mL)。