f327

INU-101 is an 11β-HSD1 inhibitor. In KKAy mice, ob ob mice, and ZDF rats, oral administration of INU-101 led to enhanced insulin sensitivity and the lowering of the fasting level of glucose in the blood. INU-101 therefore shows promise as a potential treatment for type 2 diabetes and metabolic syndrome.

F-327 is an oxytocin antagonist.

PF3274167 (Cligosiban) 是一种有效的、选择性的、高亲和力的非肽催产素受体拮抗剂。