ezetimibe-d-4

Ezetimibe-D4,a deuterium-labeled variant of Ezetimibe (T1593),functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1)and is recognized for its potent activation of Nrf2.

Ezetimibe-D4-1是Ezetimibe (T1593)的氘代物，Ezetimibe是一种有效的胆固醇吸收抑制剂和NPC1L1抑制剂，并具有Nrf2激活作用。

Ezetimibe phenoxy glucuronide-D4是2H 标记的 Ezetimibe phenoxy glucuronide (T11253)。Ezetimibe phenoxy glucuronide是Ezetimibe 的活性代谢物，具有降脂活性，抑制肠道对胆固醇的吸收。phenoxy glucuronide。Ezetimibe phenoxy glucuronide 通过减少肠道对胆固醇的吸收来降低 LDL-C。