epertinib

Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM). It displays a strong antitumor activity.

Epertinib hydrochloride (S-22611 hydrochloride) 是口服可逆的选择性EGFR、HER2和HER4抑制剂，IC50值分别为 1.48、7.15 和 2.49 nM，具有抗肿瘤活性。