dspe-peg-2-mal

DSPE-PEG2-mal is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

DSPE-PEG5000-Mal ammonium 是由 DSPE 脂质与马来酰亚胺功能基团组成的两性共轭物，常用于制备纳米结构脂质载体以实现药物递送。DSPE-PEG5000-Mal ammonium 可提高封装药物的体循环时间及胶体稳定性，其衍生物 DSPE-PEG5000-Mal 通过引入 PEG5000 链进一步改善药代动力学性质和生物相容性，为纳米医学制剂提供优化手段。