Doramectinmonosaccharide is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. Doramectin undergoes acid-catalyzed hydrolysis to form doramectinmonosaccharide.
Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysis product doramectinmonosaccharide . Doramectin undergoes one round of acid-catalyzed hydrolysis to form doramectinmonosaccharide which is then hydrolyzed again to remove the remaining saccharide unit and form doramectin aglycone.