dbconhs ester

DBCO-NHS ester 是一种 ADC 连接剂，可裂解的 3 单元 PEG，还可以用于合成抗体药物共轭物 (ADC)。

DBCO-NHS ester 2 is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs). It is a Dibenzylcyclooctyne (DBCO) derivative specifically designed for application in copper-free click chemistry [1].

DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC). It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2].

Sulfo DBCO-PEG3-NHS ester TEA 是含叠氮基团的点击化学试剂，DBCO 基团因其应变而促进高能量常用于无铜点击化学反应，NHS 酯能够与氨基酸或其他含氨基的分子结合。