chamaejasmine

Chamaejasmine could be a candidate drug for osteosarcoma and breast cancer chemoprevention, induces apoptosis in MG63 and HEp-2 cells by Akt inactivation and dephosphorylation of BAD. It inhibits Bcl-2 expression and induces Bax expression to desintegrate

Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg mL) and subsequent proliferation of human prostate cancer LNCaP cells, it blocks cell cycle progression at the G1 phase by activating the p21 protein and ultimately pro

Neochamaejasmin B 是一种提取自Stellera chamaejasme L.的双黄酮化合物。它在 C-2 C-3 和 C-2″ C-3″ 位置具有顺反几何结构。

Isochamaejasmine 分离自 S. chamaejasme L. 中分离出来，可抑制 NF-κB 活化。 Isochamaejasmine 通过抑制 Bcl-2 家族蛋白的活性诱导白血病细胞凋亡，可用于抗癌研究。

7-Methoxyneochamaejasmine A has a strong inhibitory effect on Festuca rubra L. and Medicago sativa seedlings.