cdc7in1

Cdc7-IN-1 is a highly selective and ATP competitive inhibitor of Cdc7 kinase (IC50: 0.6 nM at 1 mM ATP). It potently inhibits Cdc7 activity in cancer cells and effectively induces cell death.

Cdc7-IN-15 (Example 108) 是 cdc7激酶抑制剂，具有用于癌症研究的潜力。

Cdc7-IN-17 是CDC7的有效抑制剂，IC50值小于10 μM，可用于癌症研究。

(S)-Cdc7-IN-18, a potent CDC7 inhibitor, effectively impedes the overactivation of MCM2, a crucial tumor cell marker, induced by huCdc7 overexpression. Consequently, it inhibits the aberrant proliferation of tumor cells. This compound, exhibits promise for cancer disease research [1].

Cdc7-IN-10 是一种 Cdc7 的高效抑制剂 (IC50≤1 nM)，能够用于增殖性疾病的研究。

Cdc7-IN-11 是一种 Cdc7 的高效抑制剂 (IC50≤1 nM)，能够用于增殖性疾病的研究。