cd-73-in-5

CD73-IN-5 is a highly potent and selective small molecule inhibitor of CD73, demonstrating non-nucleotide characteristics. It exerts its inhibitory effects with a remarkable IC50 value of 19 nM.

PD-L1/CD-73-IN-1 (compound CC-5) 是一种PD-L1/CD73抑制剂，对PD-L1和CD73的IC50值分别为6 nM和0.773 μM，并能够在体内外抑制肿瘤细胞的生长。

CD73-IN-4 是高选择性的亚甲基膦酸 CD73抑制剂，对人 CD73 作用的 IC50值为 2.6 nM，在癌症免疫学中具有研究潜力。