carbovir

Carbovir, also known as (-)-Carbovir, is a nucleoside nucleotide reverse transcriptase inhibitor (NRTI) caused mitochondrial toxicity in human hepatoma carcinoma cell.

(+)-Carbovir is a nucleoside analog with increased chemical stability and increased metabolic stability.

(+)-Carbovir triphosphate is an active metabolite of Abacavir. It was used to study the molecular mechanism of inhibition and drug resistance for HIV-1 reverse transcriptase.

CNV-2197944 is a novel, small molecule, state-dependent calcium channel blocker, designed to selectively inhibit highly active Cav2.2 channels.

Carbovir triphosphate (CBV-TP) 是一种磷酸化代谢物，主要应用于人类免疫缺陷病毒（HIV）的研究。

rel-Carbovir monophosphate是2',3'-二脱氧-2',3'-二脱氢鸟苷以及Carbovir (CBV)的碳环类似物的对映体。Carbovir是一种HIV复制抑制剂，能够特异性阻止核酸前体整合到DNA中。

ent-Abacavir is an enatiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.