c20 sphingomyelin

C20 Sphingomyelin is a naturally occurring sphingolipid. Levels of C20 sphingomyelin are upregulated in the hippocampus of rats with diabetes induced by streptozotocin and in human plasma where it is positively correlated with insulin resistance in obese humans. C20 sphingomyelin is also upregulated in the liver of a mouse model of Niemann-Pick type C1 disease, a neurodegenerative cholesterol-sphingolipid lysosomal storage disorder. The plasma concentration of C20 sphingomyelin is decreased in men with prostate cancer.

C20 Sphingomyelin (d18:1/20:1) (Compound SM:20:1) 是一种鞘磷脂，可用于研究肌萎缩性侧索硬化症 (ALS) 和原发性侧索硬化症 (PLS) 等运动神经元疾病。