c178

C-178 是 STING 选择性共价抑制剂，与 Cys91 结合抑制小鼠中由不同的激活剂引起的 STING 反应。

AC-178335 is a pure somatostatin (SRIF) antagonist with an affinity constant (Ki) of 172 + - 12 nM. AC-178335 blocks SRIF inhibition of adenylate cyclase in vitro (IC50 = 5.1 + - 1.4 microM). It induces GH release when given alone (50 micrograms intraveno