boc peg4 acid

Boc-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Azido-PEG2)-N-Boc-PEG4-acid is a polyethylene glycol (PEG)-based linker specifically designed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker featuring a terminal azide group, primarily employed in PROTAC synthesis[1].

Acid-PEG4-C2-Boc is a linker compound based on polyethylene glycol (PEG) and alkyl/ether. It is utilized in the synthesis of PROteolysis TArgeting Chimeras (PROTACs) for the purpose of inhibiting the mechanistic Target of Rapamycin (mTOR)[1].

Boc-N-amido-PEG4-C3-acid is a polyethylene glycol (PEG) derived linker utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Boc-PEG4-phosphonic acid ethyl ester is a polyethylene glycol (PEG) derived linker compound employed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Boc-PEG4-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Methyl-N-(t-Boc)-PEG4-acid is a polyethylene glycol (PEG) derivative utilized as a PROTAC linker in the synthesis of PROTACs, which refers to proteolysis-targeting chimeras[1].

Boc-aminoxy-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Boc-N-bis(PEG4-acid) (Acid-apeg8-acid n-boc) 是一种属于 PEG 类的 PROTAC linker，可用于合成 PROTAC 分子。

N-(Boc-PEG5)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-derived PROTAC linker employed for PROTAC synthesis[1].

t-Boc-N-amido-PEG4-Val-Cit 是一种酶可切割的 ADC 连接子，包含 Boc 保护的胺、亲水性 PEG 间隔物以及 Val-Cit 二肽。Val-Cit 二肽能被细胞蛋白酶切割，并含有可与胺偶联形成酰胺的游离羧酸。在酸性条件下，Boc 可被去除以露出游离的一级胺，适用于各种反应，包括偶联和还原胺化。