boc peg4 acid

Boc-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Azido-PEG2)-N-Boc-PEG4-acid is a polyethylene glycol (PEG)-based linker specifically designed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker featuring a terminal azide group, primarily employed in PROTAC synthesis[1].

N-Methyl-N-(t-Boc)-PEG4-acid is a polyethylene glycol (PEG) derivative utilized as a PROTAC linker in the synthesis of PROTACs, which refers to proteolysis-targeting chimeras[1].

Acid-PEG4-C2-Boc is a linker compound based on polyethylene glycol (PEG) and alkyl ether. It is utilized in the synthesis of PROteolysis TArgeting Chimeras (PROTACs) for the purpose of inhibiting the mechanistic Target of Rapamycin (mTOR)[1].

Boc-N-amido-PEG4-C3-acid is a polyethylene glycol (PEG) derived linker utilized for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Boc-PEG4-phosphonic acid ethyl ester is a polyethylene glycol (PEG) derived linker compound employed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].

Boc-PEG4-sulfonic acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-aminoxy-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Boc-N-bis(PEG4-acid) (Acid-apeg8-acid n-boc) 是一种属于 PEG 类的 PROTAC linker，可用于合成 PROTAC 分子。

N-(Boc-PEG5)-N-bis(PEG4-acid) is a polyethylene glycol (PEG)-derived PROTAC linker employed for PROTAC synthesis[1].

t-Boc-N-amido-PEG4-Val-Cit 是一种酶可切割的 ADC 连接子，包含 Boc 保护的胺、亲水性 PEG 间隔物以及 Val-Cit 二肽。Val-Cit 二肽能被细胞蛋白酶切割，并含有可与胺偶联形成酰胺的游离羧酸。在酸性条件下，Boc 可被去除以露出游离的一级胺，适用于各种反应，包括偶联和还原胺化。