bms986313

BDP8900 is a potent and selective MRCK inhibitor, reducing substrate phosphorylation. BDP8900 leads to morphological changes in cancer cells along with inhibition of their motility and invasive character.

BMS-986313 is a RORγt Inverse Agonist with RORγt EC50 = 3.6 nM and WB EC50 = 50 nM.