bispeg4acid

Bis-PEG4-acid is a PEG PROTAC linker (PROteolysis TArgeting Chimera) used in targeted protein degradation applications.

Sulfone-Bis-PEG4-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Biotin-PEG4)-N-bis(PEG4-acid) HCl salt is a PEG Linker which may be useful in the development of antibody drug conjugates.

Methyltetrazine-amido-N-bis(PEG4-acid) 为含甲基四氮基的高效点击化学试剂.该化合物含 Tetrazine 基团和双羧酸端基,属于 PEG 衍生物,可在不需要 Cu 催化及高温条件下与含 TCO 的生物分子进行反应,通过 Diels-Alder 环加成反应(即逆电子需求 Diels-Alder 反应,iEDDA)迅速形成稳定共价键.此种反应速度快,选择性高.另外,末端羧酸可在激活剂(如 EDC 或 HATU)存在下与伯胺反应,形成酰胺键.PEG 连接增强了其在水中的溶解性.本品为试剂级,仅限研究使用.