bis-propargyl-peg-6

Bis-propargyl-PEG6 is a polyethylene glycol (PEG) derivative commonly employed as a PEG-based PROTAC linker during the synthesis of PROTACs. Its application includes the generation of polymer-linked multimers of guanosine-3', 5'-cyclic monophosphates[1].

Amino-PEG4-bis-PEG3-propargyl 是一种很具特色的点击化学试剂，它由6个单元的PEG组成，并带有可降解性质，适合用作合成抗体偶联活性分子（ADC）的链接器。该化合物包含一个Alkyne 基团，能够在铜催化下与含Azide基团的分子进行叠氮-炔环加成反应（CuAAc）。