bis-peg1-acid

Bis-PEG1-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

2-(Biotin-amido)-13-bis(carboxylethoxy)propane is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker utilized in the synthesis of PROTACs[1].

Acid-PEG1-bis-PEG3-BCN是一种可降解 (cleavable) 的含4个单元PEG的ADC linker，可用于合成抗体偶联活性分子 (ADC)。Acid-PEG1-bis-PEG3-BCN 是一种点击化学试剂，含有BCN基团，能够与含有Azide基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC)。