bis-mal-peg-3

Bis-Mal-PEG3 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Mal-bis-PEG3-DBCO是一种可降解 (cleavable) 的3个单元PEG的ADC linker，适用于合成抗体偶联活性分子 (ADC)。作为一种点击化学试剂，Mal-bis-PEG3-DBCO含有DBCO基团，可与含有Azide基团的分子进行菌株促进的炔-叠氮环加成反应 (SPAAC)。