bis-aminooxy-peg-1

Bis-aminooxy-PEG1 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a polyethylene glycol (PEG) derivative commonly employed as a PEG-based linker in the manufacturing of proteolysis-targeting chimeras (PROTACs)[1].

N-(Aminooxy-PEG3)-N-bis(PEG4-Boc) is a polyethylene glycol (PEG)-based linker primarily utilized in PROTAC synthesis for the development of proteolysis-targeting chimeras (PROTACs)[1].

N-(t-Boc-Aminooxy-PEG2)-N-bis(PEG3-propargyl) is a polyethylene glycol (PEG) derivative specifically designed as a linker for PROTAC synthesis [1].

Aminooxy-PEG2-bis-PEG3-BCN 作为一种含有五个单元 PEG 的可降解（cleavable）ADC linker，主要应用于合成抗体偶联活性分子（ADC）。此外，Aminooxy-PEG2-bis-PEG3-BCN 也是一种点击化学试剂，其BCN基团能与含Azide基团的分子通过菌株促进的炔-叠氮环加成反应（SPAAC）进行反应。