bis peg3 t butyl ester

Bis-PEG3-t-butyl ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Azido-PEG3)-N-bis(PEG1-t-butyl ester) is a polyethylene glycol (PEG)-based PROTAC linker utilized for the synthesis of PROTACs[1].

Benzyl-N-bis(PEG3-Boc) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(t-Butyl ester-PEG3)-N-bis(PEG3-amine) 是一种 PEG 试剂，在存在 EDC 或 HATU 的条件下，可与活化的 NHS 酯或羧酸进行反应。叔丁基在酸性环境中可以去保护。亲水性 PEG 间隔物能够提高化合物在水性介质中的溶解性。