benzyl-peg5-azide

Benzyl-PEG5-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Aldehyde-benzyl-PEG5-alkyne 是一种 PEG 类的 PROTAC linker，可用于合成 PROTAC 分子。作为一种点击化学试剂，它拥有 Alkyne 基团，能够与含有 Azide 基团的分子进行铜催化的叠氮-炔环加成反应 (CuAAc)。