benzyl peg5 azide

Benzyl-PEG5-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Alkyne-PEG5-SNAP 是一种点击化学试剂,具备炔基团.该化合物能与苄基鸟嘌呤(BG)发生炔基共轭反应.BG能与SNAP-标签(一种多肽蛋白标记技术)特异性地快速反应,赋予SNAP融合蛋白以不可逆和共价的性质,并提供额外的炔基功能以便进一步的偶联反应.此外,Alkyne-PEG5-SNAP 可通过与含Azide基团的分子进行铜催化的叠氮-炔环加成反应(CuAAc) 进行反应.