azido-peg-2-alcohol

Azido-PEG2-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Azido-PEG5-alcohol, a non-cleavable 5 unit polyethylene glycol (PEG) ADC linker, finds application in the synthesis of antibody-drug conjugates (ADCs)[1]. Additionally, it serves as a PEG-based PROTAC linker for the synthesis of PROTACs[2].

Azido-PEG6-alcohol is a polyethylene glycol (PEG)-based PROTAC linker utilized in PROTAC synthesis[1]. It also functions as a non-cleavable PEG linker consisting of six units, specifically employed in the synthesis of antibody-drug conjugates (ADCs)[2].