avermectin b1a

Avermectin B1a 是能够使线虫瘫痪的一种抗寄生虫剂。

Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a . It hyperpolarizes P. crassipes muscle fibers with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a aglycone decreases survival of C. elegans (MAC = 0.1 μM). In vivo, avermectin B1a aglycone prevents seizures induced by pentylenetetrazole in mice (ED50 = 43.9 mg/kg) without inducing deficits in rotarod performance.

Avermectin B1a monosaccharide is a macrolide anthelmintic and monosaccharide form of avermectin B1a . It is lethal to C. elegans with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a monosaccharide also stimulates conductance in isolated shore crab muscle.

Avermectin B1a in Acetonitrile (Standard) 是一种可用于分析的标准物质，通常用作 Avermectin B1a 研究和分析中参考的标准样品。Avermectin 是一种从从土壤中分离出来发酵链霉菌中提取的化合物，可降低 Caspase-8 和 Bcl-2 的表达。

Avermectin B1 是驱虫杀虫剂。

2-epi-Abamectin, a degradation product of abamectin, exhibits toxicity towards the two-spotted spider mite in contact assays, possessing an LC50 value of 4 ppm. This indicates it is approximately 100-fold less potent than its precursor, abamectin.

Eprinomectin B1a, composing over 90% of the antiparasitic agent eprinomectin, is a primary component alongside eprinomectin B1b, which constitutes less than 10%. This compound is part of the avermectin family, used as insecticides and anthelmintics.

Ivermectin B1a 是 Avermectin B1a 的一种衍生物，是 Ivermectin 的主要成分。Ivermectin 是广谱的抗寄生虫剂。Ivermectin 也是抗 SARS-CoV-2 COVID-19 的候选药物。