antisauvagine30

Potent, selective and competitive corticotropin-releasing factor CRF2 receptor antagonist (Kd values are 1.4 and 153.6 nM for binding to mouse CRF2β and rat CRF1 receptors respectively). Inhibits sauvagine-stimulated cAMP accumulation in HEK-mCRF2β cells

Antisauvagine-30 TFA (aSvg-30 TFA) 是有效的、高度选择性的、竞争性的CRF2受体的多肽拮抗剂。Antisauvagine-30 TFA 对 mCRFR2β 和CRFR1的Kd 值分别为1.4 nM 和150 nM。