angiotensin i/ii (1 6) (tfa)

Angiotensin I II (1-6) TFA is a chemical compound comprising amino acids 1-6. It is derived from the Angiotensin I II peptide, which is formed by the cleavage of the precursor angiotensinogen by renin. The resulting Angiotensin I is then hydrolyzed by angiotensin-converting enzyme (ACE) to produce biologically active Angiotensin II. Angiotensin II has been extensively studied for its potential applications in the treatment of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy[1][2][3].

Saralasin ([Sar1,Ala8] Angiotensin II) TFA，血管紧张素 II (angiotensin II) 的八肽衍生物，作为竞争性血管紧张素 II 受体 (angiotensin II receptor) 拮抗剂，其Ki值达0.32 nM（涵盖74%的结合位点），显示出部分激动剂特性。适应于肾血管性高血压、肾素依赖性（血管紧张素原性）高血压的研究。

Angiotensin 1 2 (1-9) TFA(34273-12-6(free base)) 含有从血管紧张素 I II 肽转化而来的氨基酸 1-9。