Aminooxy-PEG1-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Boc-aminooxy-PEG1-propargyl is a polyethylene glycol (PEG)-based linker commonly employed in the synthesis of proteolysis targeting chimeras (PROTACs)[1].