amino peg5 amine

Amino-PEG5-amine, a PEG-based linker containing 5 units, is utilized in PROTAC synthesis.

Tri(Amino-PEG5-amide)-amine is a polyethylene glycol (PEG) derivative serving as a PEG-based proteolysis targeting chimera (PROTAC) linker, facilitating the synthesis of PROTACs[1].

Carboxy-Amido-PEG5-N-Boc 是一种带有末端羧酸和 Boc 保护氨基的 PEG 连接体。其亲水性的 PEG 间隔物能够提升在水性介质中的溶解度。在活化剂（例如 EDC、HATU）存在下，末端羧酸能够与一级胺基团反应，生成稳定的酰胺键。Boc 基团在温和酸性条件下可脱保护，产生游离胺。