alkyne peg4 ss peg4 alkyne

Alkyne-PEG4-SS-PEG4-alkyne is an eight-unit polyethylene glycol (PEG) linker, designed for antibody-drug conjugates (ADCs) synthesis, that can be cleaved. This linker serves as a connection between the antibody and the drug, allowing for controlled release upon specific conditions [1].

Biotin-PEG4-SS-azide 是一种可降解的、生物素标记的 ADC linker，用于合成 ADCs。作为一种点击化学试剂，它含有 Azide 基团，可以与含有 Alkyne 基团的分子发生铜催化的叠氮-炔环加成反应（CuAAc)；也能与含有 DBCO 或 BCN 基团的分子发生菌株促进的炔-叠氮环加成反应 (SPAAC)。