Ald-Ph-amido-PEG3-NHSester is a non-cleavable 3-unit PEG linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). It is utilized as a chemical compound in connecting antibodies and drugs, forming stable conjugates.
Ald-Ph-PEG24-NHSester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.