ald 8

Ald-CH2-PEG8-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Ald-Ph-PEG4-bis-PEG4-propargyl是一种可降解(cleavable)的含8个单元PEG的ADC linker，可用于合成抗体偶联活性分子(ADC)。Ald-Ph-PEG4-bis-PEG4-propargyl是一种点击化学试剂，含有Alkyne基团，可以与含有Azide基团的分子进行铜催化的叠氮-炔环加成反应(CuAAc)。