ajmaline

Ajmaline (Cardiorythmine) 是一种钠通道阻断剂，属于1A 类抗心律失常剂。Ajmaline 阻断 HERG 电流，在 HEK 细胞的 IC50为 1 μM，爪蟾卵母细胞的IC50为 42.3 μM。Ajmaline 在室性心动过速方面具有研究价值。

Ajmaline hydrochloride is an alkaloid found in the root of Rauwolfia serpentina, and other plant sources. It is a class of Ia antiarrhythmic agent that apparently works by changing the shape and threshold of cardiac action potentials.

(+)-Isoajmaline 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4260，CAS号为 6989-79-3。

Lorajmine, a monochloroacetyl derivative of ajmaline, is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases.

Prajmalium, a derivative of the rauwolfia alkaloid AJMALINE, is an anti-arrhythmia agent but may cause liver damage.

Prajmalium bitartrate, a derivative of the rauwolfia alkaloid AJMALINE, is an anti-arrhythmia agent but may cause liver damage.

Vinorine is a direct biosynthetic precursor along the complex pathway to the monoterpenoid indole alkaloid ajmaline, an antiarrhythmic drug from the Indian medicinal plant Rauvolfia serpentina.