Prosaikogenin A, a triterpene saponin extracted from Clinopodium chinense, exhibits notable platelet aggregation promotion activity, indicated by an EC 50 value of 12.2 μM.
Tibesaikosaponin V 是一种三萜双糖苷,可从北柴胡 (Bupleurum chinense DC) 的根的甲醇提取物中分离得到。Tibesaikosaponin V (TKV) 是一种三萜双糖苷,可从 Bupleurum chinense DC 根的甲醇提取物中分离得到。Tibesaikosaponin V 抑制脂质积累和甘油三酯含量的发生,对脂肪细胞没有细胞毒性。Tibesaikosaponin V 抑制核转录因子的 mRNA 表达,例如过氧化物酶体增殖物激活受体 γ (PPARγ) 和 CCAAT 增强子结合蛋白 α (C EBPα)。Tibesaikosaponin V 抑制 3T3-L1 前脂肪细胞分化。Tibesaikosaponin V 可用于肥胖及其相关代谢紊乱的研究。
Saikogenin D possesses a dual effect: an inhibition of A23187-induced PGE2 production without a direct inhibition of cyclooxygenase activity; and an elevation of [Ca2+]i that is attributed to Ca2+ release from intracellular stores. Saikogenin D has immuno