aflatoxin g1

Aflatoxin G1是一种由黄曲霉（Aspergillus flavus）和寄生曲霉（Aspergillus parasiticus）产生的霉菌毒素，具有肝毒性、致畸性、免疫抑制性和致癌性,主要存在于受污染的谷物中。黄曲霉毒素 G1可抑制RNA聚合酶活性，影响RNA和蛋白质合成，并对肝脏和肾脏造成损伤.

Aflatoxin G1 9,10-epoxide is a biochemical.

Aflatoxin G1-13C17is intended for use as an internal standard for the quantification of aflatoxin G1by GC- or LC-MS. Aflatoxin G1is a mycotoxin that has been found inA. terricola.1In vivo, aflatoxin G1is lethal to ducklings (LD50= 1.18 mg kg).2It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg animal, respectively. Aflatoxin G1also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase, NADH oxidase, α-glycerophosphate dehydrogenase, isocitrate dehydrogenase, and malate dehydrogenase in rats.3 1.Moubasher, A.H., el-Kady, I.A., and Shoriet, A.Toxigenic Aspergilli isolated from different sources in EgyptAnn. Nutr. Aliment.31(4-6)607-615(1977) 2.Wogan, G.N., Edwards, G.S., and Newberne, P.M.Structure-activity relationships in toxicity and carcinogenicity of aflatoxins and analogsCancer Res.31(12)1936-1942(1971) 3.Bai, N.J., Pai, M.R., and Venkitasubramanian, T.A.Mitochondrial function in aflatoxin toxicityIndian J. Biochem. Biophys.14(4)347-349(1977)

Aflatoxin Total in cotton seed (Standard)（基体 棉籽中黄曲霉毒素总量标准品)是用于检测食品和饲料中黄曲霉毒素总量（包括B1、B2、G1和G2）的参考物质,这些毒素是由黄曲霉和寄生曲霉产生的次级代谢产物。黄曲霉毒素具有强毒性，对肝脏、肾脏等器官危害极大，是I类致癌物。

Aflatoxin M1, a significant metabolite of Aflatoxin B1, is a mycotoxin synthesized by Aspergillus flavus and Aspergillus parasiticus fungi. Toxicity levels of Aflatoxins follow the order: Aflatoxin B1 > Aflatoxin M1 > Aflatoxin G1 > Aflatoxin B2 > Aflatoxin M2 > Aflatoxin G2.