achn-975 tfa

ACHN-975 TFA是一种选择性的细菌酶LpxC的抑制剂，具有nM级别的活性。ACHN-975具有抗菌活性，对多种革兰氏阴性菌的MIC值低于1 μg/mL。

ACHN-975 is a highly potent and selective LpxC inhibitor, demonstrating subnanomolar inhibitory activity. It effectively targets a broad spectrum of gram-negative bacteria, with low minimum inhibitory concentration (MIC) values (≤1 μg/mL)[1].