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  • Ambroxol-D5
    T711431246818-80-3
    Ambroxol-D5 is intended for use as an internal standard for the quantification of ambroxol by GC- or LC-MS. Ambroxol (T0920) is an expectorant and active metabolite of bromhexine. It decreases short-circuit currents in electrically stimulated isolated canine tracheal epithelial cells when applied submucosally. Ambroxol (T0920)decreases IL-13-induced production of mucin 5AC (MUC5AC)in primary human airway epithelial cells and inhibits IL-13-induced decreases in the mucociliary transport rate of endogenous particles in the same cells. Ambroxol (T0920)increases phenol red secretion,a marker of expectorant activity,in mice when administered at doses of 30,60,or 120 mg/kg. Formulations containing ambroxol have been used in the treatment of acute or chronic respiratory conditions.
    • ¥ 10600
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