Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T70654 |
Ciprokiren
|
Others | Others |
Ciprokiren is a renin inhibitor discovered by Roche. Ciprokinen inhibited human renin in a buffer and human plasma with an IC50 of 0.07 and 0.65 nmol/L, respectively. In animal models, acute and chronic administration of ciprokinen lead to a reduction in arterial blood pressure. Development of ciprokinen was discontinued at a preclinical stage. |