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Targets Recommended: Others

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Cat. No. Product Name Target Signaling Pathways
T71736 AMG-628, (R)-

Others Others
AMG-628, (R)- is the R isomer of AMG-628 --- a potent, ATP-competitive inhibitor of Raf kinases. AMG-628 displays selectivity for Raf kinases and inhibits activation of tyrosine protein kinases such as VEGFR2, Lyn, Flt1 and Fms. AMG-628 has shown to inhibit growth, and induces cell cycle arrest and apoptosis in colon and melanoma cell lines with the B-RafV600E mutation.
T68523 AMG-628, (S)-

Others Others
AMG-628, (S)-, is the S isomer of AMG-628 --- a potent, ATP-competitive inhibitor of Raf kinases. AMG-628 displays selectivity for Raf kinases and inhibits activation of tyrosine protein kinases such as VEGFR2, Lyn, Flt1 and Fms. AMG-628 has shown to inhibit growth, and induces cell cycle arrest and apoptosis in colon and melanoma cell lines with the B-RafV600E mutation.
T29973 AMG-628

AMG628,AMG 628,CHEMBL226574,UNII-28J966TN3X

Others Others
AMG-628 is an effective and ATP-competitive RAF kinase inhibitor. AMG-628 has been shown to inhibit growth and induce cell cycle arrest and apoptosis in colon and melanoma cell lines with B-RAFV600E mutations.

化合物

AMG-628, (R)-
Cat.No: T71736
Synonym:
Target: Others
AMG-628, (S)-
Cat.No: T68523
Synonym:
Target: Others
AMG-628
Cat.No: T29973
Synonym: AMG628,AMG 628,CHEMBL226574,UNII-28J966TN3X
Target: Others
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