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TargetMol产品目录中 "

7-dehydrocholesterol

"的结果
  • 抑制剂&激动剂
    7
    TargetMol | Inhibitors_Agonists
  • 重组蛋白
    1
    TargetMol | Recombinant_Protein
  • 天然产物
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    TargetMol | Natural_Products
  • 7-Dehydrocholesterol
    Provitamin D3, 7-DHC, 7-去氢胆固醇
    T4923434-16-2
    7-Dehydrocholesterol (Provitamin D3) 是合成胆固醇和维生素 D3的前体。7-Dehydrocholesterol 下调培养的 Smith-Lemi-Opitz 综合征皮肤成纤维细胞中的胆固醇生物合成。
    • ¥ 343
    现货
    规格
    数量
  • AY 9944
    T14362366-93-8In house
    AY 9944 是特异性的胆固醇生物合成抑制剂。它抑制 7- 脱氢胆固醇 Δ7- 还原酶 (IC50:13 nM),导致胆固醇不足和 7DHC 积累。在高剂量下,它可在培养的胚胎中抑制固醇 Δ7-Δ8 异构酶,造成胆固醇 8-en-3β-ol 的积累。
    • ¥ 375
    现货
    规格
    数量
  • Peraclopone
    T6821996164-19-1
    Peraclopone is a hypolidemic drug. It is an inhibitor of 7-Dehydrocholesterol reductase. Peraclopone potently inhibits the final step in cholesterol biosynthesis. Feeding this agent to rats leads to a rapid replacement of membrane cholesterol with its immediate precursor 7-dehydrocholesterol, and a dramatic reduction in plasma sterol concentration. Peraclopone caused a dose-dependent decrease in cholesterol and a concomitant accumulation of provitamin D3 (7-dehydrocholesterol) in the skin, which is accompanied by an increase in the plasma level of 25-hydroxyvitamin D3. Treatment with peraclopone dramatically alters membrane sterol content in many membranes including the microvillus membrane of both the jejunum and ileum. In the jejunal microvillus membrane a major change in chemical composition occurred, presumably in response to the alteration in membrane sterol. The net result was a significant decline in both the static and dynamic component of membrane fluidity.
    • ¥ 10600
    6-8周
    规格
    数量
  • BM 15766 sulfate
    T8285386621-94-5
    BM 15766 sulfate是一种7-脱氢胆固醇δ7-还原酶的抑制剂,具有降低血浆胆固醇水平的作用,属于降血脂剂类药物。
    • 待询
    5日内发货
    规格
    数量
  • Pyrocholecalciferol
    T7420810346-43-7
    Pyrocholecalciferol 一种维生素 D 类似物,由 7-脱氢胆固醇 (7-DHC) 的光化学转化产生。
    • 待询
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  • 5-Dehydroepisterol
    T1016723582-83-4
    5-Dehydroepisterol is an episterol derivative with anti-fungal activities. It can be formed by C-5 sterol desaturase and converted into 24-methylenecholesterol by 7-dehydrocholesterol reductase.
    • ¥ 10600
    6-8周
    规格
    数量
  • Boxidine
    T7156210355-14-3
    Boxidine inhibits the transformation of 7-dehydrocholesterol to cholesterol & also inhibits sterol absorption.
    • ¥ 10600
    6-8周
    规格
    数量