3 obaa

AM-9635 is a potent and selective PI3Kδ inhibitor. AM-9635 showes good cellular potency (in vitro pAKT IC50 = 4.2 nM ). AM-96352 inhibits KLH-specific IgG and IgM in a dosedependent manner AM-9635 is well tolerated at all doses and exhibits significantly reduced IgG and IgM specific antibodies . PI3Kα and PI3Kβ are ubiquitously expressed and play a role in cell growth, division, and survival.

3-(4-Octadecylbenzoyl)acrylic acid 是一种有效的广谱磷脂酶 A2 (PLA2) 抑制剂。它通过阻止花生四烯酸从细胞膜磷脂中的释放，切断了前列腺素和白三烯的生物合成级联，在急性炎症和组织损伤模型中表现出极强的抗炎活性。

OBAA (3-(4-Octadecylbenzoyl)acrylic acid) 是一种有效的广谱 PLA2 抑制剂。它通过阻断花生四烯酸的级联反应发挥显著的抗炎活性，常用于急性炎症模型及信号传导路径的研究。