3 o methylquercetin tetraacetate

Quercetin 3-O-methyl ether is a potent phosphodiesterase (PDE)3 4 inhibitor, it has potential for treating asthma against ovalbumin-induced airway hyperresponsiveness.

3-O-Methylquercetin 是分离自植物Rhamnus nakaharai 的天然产物，可抑制总 cAMP 和cGMP-phosphodiesterase (PDE)。它对PDE1、PDE5、PDE 和PDE4的IC50分别是31.9 μM、86.9 μM、18.6 μM 和1.6 μM。