183321-74-6

Erlotinib (CP358774) 是一种 EGFR 一代抑制剂，抑制 EGFR 19 Del 和 L858R 突变。Erlotinib 具有抗肿瘤活性，用于治疗 EGFR 突变的非小细胞肺癌。Erlotinib 用药会产生 EGFR C797S 耐药突变。

Erlotinib is a directly acting inhibitor EGFR tyrosine kinase inhibitor with an IC50 of 2 nM for human EGFR. Erlotinib-D6 is a deuterium labeled Erlotinib (T0373).

Erlotinib-13C6 is a 13C-labeled Erlotinib. Erlotinib (T0373) is a directly acting EGFR tyrosine kinase inhibitor,with an IC50 of 2 nM for human EGFR[1].