17924-92-4

Zearalenone (F2 toxin) 是真菌毒素，主要由食物和饲料中的 Fusarium 产生。它会引起幼龄母猪乳房发育早熟或其它雌激素效应。它在猪、牛、羊体内具有雌激素活性，急性毒性低。

Zearalenone-13C18 is intended for use as an internal standard for the quantification of zearalenone by GC- or LC-MS. Zearalenone (T5625) is a mycotoxin that has been found inFusariumand has estrogenic activities.1It binds to human estrogen receptor α (ERα)and ERβ (IC50s = 9 and 5.8 nM,respectively).2Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.3Zearalenone (1.5-5 mg/kg of diet)induces hyperestrogenism in pigs. It also induces degeneration of meiotic chromatin in oocytes and reduces fertility in pigs when administered at a dose of 200 μg/kg.4Zearalenone has been found as a contaminant in wheat,maize,and barley and livestock feeds.3,4

rac Zearalenone-D6是rac Zearalenone (T5625)的氘代化合物。