170809-51-5 free base

Astressin acetate 是促肾上腺皮质激素释放因子 (CRF) 的拮抗剂，对 CRF 结合蛋白具有低亲和力，对克隆垂体受体具有高亲和力 (Ki = 2 nM)。

Astressin is an amino-terminal truncated analog of CRF that retains high affinity binding to the extracellular domain of the receptor and is believed to act as a neutral competitive antagonist of receptor activation.