1 methylguanosine

1-Methylguanosine (N1-Methylguanosine) 是 RNA 降解产生的甲基化核苷，可作为肿瘤标志物。

3'-Deoxy-N1-methylguanosine is a Nucleoside Derivative - 3'-Modified nucleoside, N-Methylated alkylated nucleoside;3'-Deoxy nucleoside.

2'-Deoxy-N1-methylguanosine is a Nucleoside Derivative - N-Methylated nucleoside.

7-Methylguanosine 5’-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues[1]. 7-Methylguanosine 5’-diphosphate sodium inhibits binding of eukaryotic initiation factors to reovirus capped mRNA and complex formation involving uncapped mRNA or 18 S rRNA[1].T. brucei mRNA decapping enzyme (TbDcp2) that cleaves 7-Methylguanosine 5’-diphosphate sodium from capped RNA to generate pRNA, a substrate for TbCe1[2]. [1]. Sonenberg N, et al. Nonspecific effect of m7GMP on protein-RNA interactions. J Biol Chem. 1978;253(19):6630-6632.[2]. Ignatochkina AV, et al. The messenger RNA decapping and recapping pathway in Trypanosoma. Proc Natl Acad Sci U S A. 2015;112(22):6967-6972.

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium 是体外 RNA 转录中使用的二核苷酸帽类似物。