γlinolenic acid ethyl ester

γ-Linolenic acid ethyl ester (Ethyl γ-linolenate) 是一种白三烯 B 受体 4(LTB4)的拮抗剂，具有潜在的抗炎作用。

Ethyl dihomo-γ-linolenic acid ethyl ester (ethyl DGLA), an ω-6 fatty acid intermediate ester form, elevates prostaglandin E1(PGE1) and PGE2 secretion in rabbit renal papilla when administered dietarily at a dosage of 1 g/kg per day for 25 days. Additionally, this dosage of ethyl DGLA increases triglyceride levels and enhances the proportion of 20:3ω6 and 20:4ω6 phospholipids in the renal medulla of rabbits. Ethyl DGLA formulations have been employed in managing eczema and inflammatory disorders.

Ethyl linolenate 为脂肪酸乙酯，具有抑制细胞黑色素合成的抗黑色素生成活性，其 IC50 为 70 μM。其可抑制 forskolin 刺激的黑色素生成并降低酪氨酸酶活性，支持其在色素障碍研究及皮肤美白机制探索中的应用价值。