β amyloid (1 43)(human)

The amyloid β-protein is a 39- to 43-amino acid polypeptide that is the primary constituent of senile plaques and cerebrovascular deposits in Alzheimer's disease and Down's syndrome. Additionally it acts as an inhibitor of the ubiquitin-dependent protein degradation in vitro.

β-Amyloid (1-43)(human) TFA 相较于 Aβ1-42 显示出更高的聚集倾向和毒性。它与 sAPPα 和 sAPPβ 有关联，且作为一种潜在的新型阿尔茨海默病(AD)生物标志物，具备与其他已知生物标志物相似的应用潜力。