α-Linolenicacid (ALA) is an essential fatty acid found in leafy green vegetables. ALA, as part of a low saturated fat diet, helps prevent cardiovascular disease. ALA decreases blood pressure, serum cholesterol levels, and platelet aggregation.
Ethyl dihomo-γ-linolenicacid ethyl ester (ethyl DGLA), an ω-6 fatty acid intermediate ester form, elevates prostaglandin E1(PGE1) and PGE2 secretion in rabbit renal papilla when administered dietarily at a dosage of 1 g kg per day for 25 days. Additionally, this dosage of ethyl DGLA increases triglyceride levels and enhances the proportion of 20:3ω6 and 20:4ω6 phospholipids in the renal medulla of rabbits. Ethyl DGLA formulations have been employed in managing eczema and inflammatory disorders.
1,2,3-Tri-γ-linolenoyl glycerol, a polyunsaturated triacylglycerol featuring γ-linolenoyl side chains at the C-1, C-2, and C-3 positions, occurs in multiple plant species such as blackcurrant, redcurrant, and borage.